Hello everyone, i have controlled released Oxycodone HCL made by SANDOZ and i need to extract active ingredient so it will work as immediate release formulation.
I found what ingredients they use on their website:
medium chain triglycerides
castor oil - hydrogenated
colloidal anhydrous silica
what i tried to do so far is to get the main active ingredient out (Oxycodone CHL)
I heated up alkaline 8+ water in a pot till it is about body temp 37-38 Celsius
waited around for a bit and my pill splits in half and i get this "core" looking peace (which i think was Oxycodone HCL)
I then tried to dissolve it in water and it wouldn't, also
I tried to dissolve it in 37% ethanol and it Wont dissolve.
At the end i ended up just taking it orally but it would not do a trick it still acts like slow acting medication....
How do i make it to instant release?
people who will not bother to reply to this question
HUGE THANK YOU!